2,4-dichlorophenoxyacetic acid-induced oxidative stress: Metabolome and membrane modifications in Umbelopsis isabellina, a herbicide degrader
نویسندگان
چکیده
منابع مشابه
Oxidative Stress Induced by the 2,4-Dichlorophenoxyacetic Herbicide
Phenoxyacetic herbicides constitute one of the largest groups of herbicides sold in the world. Among them, since 1946, 2,4-Dichlorophenoxyacetic acid (2,4-D), whose structural formula is shown in Fig. 1, has been the most used. Nowadays, new formulations of 2,4-D are continuously made available. In fact, there are over 600 2,4-D products currently on the market. For over 60 years, 2,4-D has bee...
متن کاملOxidative Stress as a Possible Mechanism of Toxicity of the Herbicide 2,4- Dichlorophenoxyacetic Acid (2,4-D)
Chlorophenoxy herbicides are widely used in agriculture and forestry, for the control of broad-leaved weeds in pastures, cereal crops, as well as along public rights of way. Structurally, these herbicides consist of a simple aliphatic carboxylic acid moiety attached to a chlorine-substituted aromatic ring via an ether linkage. One of the most commonly used herbicides of this type is 2,4-dichlor...
متن کاملElimination and detoxification of 2,4-D by Umbelopsis isabellina with the involvement of cytochrome P450
The chemical 2,4-dichlorophenoxyacetic acid (2,4-D) is used in agriculture as a herbicide. Its intensive use has an adverse effect on the environment. This study involved examining the degradation of 2,4-D compound by the filamentous fungus Umbelopsis isabellina. After 5 days of incubation, 98% of the herbicide (added at 25 mg L-1) was found to be removed. The elimination of 2,4-D by U. isabell...
متن کاملHypoglycemic Effect of Herbicide 2,4-Dichlorophenoxyacetic Acid (2,4-D)
Ivan Mikov1, Velibor Vasović2, Aleksandra Mikov3, Svetlana Goločorbin-Kon4, Karmen Stankov5 and Momir Mikov2 1Institute of Occupational Health, Medical Faculty, Futoška 121, 21000 Novi Sad, Serbia ([email protected]) 2Department of Pharmacology, Toxicology and Clinical Pharmacology, Medical Faculty, Futoška 121, 21000 Novi Sad, Serbia 3Institute of Child and Youth Health Care, Medical Faculty, Fut...
متن کاملEarly transcriptional response of Saccharomyces cerevisiae to stress imposed by the herbicide 2,4-dichlorophenoxyacetic acid.
The global gene transcription pattern of the eukaryotic experimental model Saccharomyces cerevisiae in response to sudden aggression with the widely used herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) was analysed. Under acute stress, 14% of the yeast transcripts suffered a greater than twofold change. The yeastract database was used to predict the transcription factors mediating the response...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2018
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0199677